Cargando…

Hypernatremia and intracranial pressure: more questions than answers

The observational literature suggests that hypernatremia is associated with worse outcomes in patients with traumatic brain injury. In a previous issue of Critical Care, Wells and colleagues add to this literature by failing to show an association between hypernatremia and reduced intracranial press...

Descripción completa

Detalles Bibliográficos
Autores principales: Griesdale, Donald EG, Sekhon, Mypinder S, Henderson, William R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057414/
https://www.ncbi.nlm.nih.gov/pubmed/23294598
http://dx.doi.org/10.1186/cc11888
Descripción
Sumario:The observational literature suggests that hypernatremia is associated with worse outcomes in patients with traumatic brain injury. In a previous issue of Critical Care, Wells and colleagues add to this literature by failing to show an association between hypernatremia and reduced intracranial pressure. However, we must bear in mind many limitations of observational methods before eliminating hyperosmolar therapy from our armamentarium.