Cargando…

Insights from Computational Modeling in Inflammation and Acute Rejection in Limb Transplantation

Acute skin rejection in vascularized composite allotransplantation (VCA) is the major obstacle for wider adoption in clinical practice. This study utilized computational modeling to identify biomarkers for diagnosis and targets for treatment of skin rejection. Protein levels of 14 inflammatory media...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wolfram, Dolores, Starzl, Ravi, Hackl, Hubert, Barclay, Derek, Hautz, Theresa, Zelger, Bettina, Brandacher, Gerald, Lee, W. P. Andrew, Eberhart, Nadine, Vodovotz, Yoram, Pratschke, Johann, Pierer, Gerhard, Schneeberger, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057425/ https://www.ncbi.nlm.nih.gov/pubmed/24926998 http://dx.doi.org/10.1371/journal.pone.0099926

Ejemplares similares

Differentiation between Acute Skin Rejection in Allotransplantation and T-Cell Mediated Skin Inflammation Based on Gene Expression Analysis
por: Wolfram, Dolores, et al.
Publicado: (2015)

Mechanisms and Mediators of Inflammation: Potential Models for Skin Rejection and Targeted Therapy in Vascularized Composite Allotransplantation
por: Hautz, Theresa, et al.
Publicado: (2012)

Subcutaneous administration of a neutralizing IL‐1β antibody prolongs limb allograft survival
por: Hautz, Theresa, et al.
Publicado: (2018)

Cardiac Arrest Disrupts Caspase-1 and Patterns of Inflammatory Mediators Differently in Skin and Muscle Following Localized Tissue Injury in Rats: Insights from Data-Driven Modeling
por: Starzl, Ravi, et al.
Publicado: (2015)

Long‐term outcome after hand and forearm transplantation – a retrospective study
por: Hautz, Theresa, et al.
Publicado: (2020)

Review of the Early Diagnoses and Assessment of Rejection in Vascularized Composite Allotransplantation
por: Starzl, Ravi, et al.
Publicado: (2013)

Editorial: Immunology of machine perfused organs and tissues
por: Hautz, Theresa, et al.
Publicado: (2022)

Hide‐and‐seek: Neurotropic squamous cell carcinoma of the periorbital region – a series of five cases and review of the literature
por: Morandi, Evi M., et al.
Publicado: (2021)

Defining chronic rejection in vascularized composite allotransplantation—The American Society of Reconstructive Transplantation and International Society of Vascularized Composite Allotransplantation chronic rejection working group: 2018 American Society of Reconstructive Transplantation meeting report and white paper Research goals in defining chronic rejection in vascularized composite allotransplantation
por: Kaufman, Christina L, et al.
Publicado: (2020)

Resection of Skin Cancer Resulting in Free Vascularized Tissue Reconstruction: Always a Therapeutic Failure?
por: Rauchenwald, Tina, et al.
Publicado: (2023)

Bioenergetic and Cytokine Profiling May Help to Rescue More DCD Livers for Transplantation
por: Hofmann, Julia, et al.
Publicado: (2023)

Cell-Based Regeneration and Treatment of Liver Diseases
por: Hofmann, Julia, et al.
Publicado: (2021)

Dynamics of Systemic Inflammation as a Function of Developmental Stage in Pediatric Acute Liver Failure
por: Vodovotz, Yoram, et al.
Publicado: (2021)

Machine Perfusion of Porcine Livers with Oxygen-Carrying Solution Results in Reprogramming of Dynamic Inflammation Networks
por: Sadowsky, David, et al.
Publicado: (2016)

Sodium Sulfite Exacerbates Allograft Vasculopathy and Affects Tryptophan Breakdown in Murine Heterotopic Aortic Transplantation
por: Sucher, Robert, et al.
Publicado: (2019)

Is It All about Surface Topography? An Intra-Individual Clinical Outcome Analysis of Two Different Implant Surfaces in Breast Reconstruction
por: Schoberleitner, Ines, et al.
Publicado: (2023)

Inflammatory signals and network connections implicate cell-mediated immunity in chronic venous insufficiency
por: Vodovotz, Lena, et al.
Publicado: (2021)

Combining Theoretical and Experimental Techniques to Study Murine Heart Transplant Rejection
por: Arciero, Julia C., et al.
Publicado: (2016)

Analysis of Serum Inflammatory Mediators Identifies Unique Dynamic Networks Associated with Death and Spontaneous Survival in Pediatric Acute Liver Failure
por: Azhar, Nabil, et al.
Publicado: (2013)

Simple, but effective: Nasal splinting for airway securement in free flap reconstruction following orbital exenteration
por: Rauchenwald, Tina, et al.
Publicado: (2021)

Functional Shoulder Outcome and Quality of Life Following Modified Muscle-Sparing Pectoralis Major Flap Surgery
por: Rauchenwald, Tina, et al.
Publicado: (2021)

Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream
por: Wilk, Michael, et al.
Publicado: (2011)

Vasculitides and occluding vasculopathies, challenges in recognizing histopathological patterns, and their solutions
por: Wilk, Michael, et al.
Publicado: (2023)

Recurrence of Hepatocellular Carcinoma After Liver Transplantation is Associated with Episodes of Acute Rejections
por: Gül-Klein, Safak, et al.
Publicado: (2021)

Abstract QS22: A Novel And Unexpected Role Of Donor T Cells In The Efficacy Of Tolerogenic Therapies For Transplant Rejection
por: Lozano, Marcos Iglesias, et al.
Publicado: (2019)

Rotational Transport of Islets: The Best Way for Islets to Get around?
por: Oberhuber, Rupert, et al.
Publicado: (2013)

Bar code reader – an algorithmic approach to cutaneous occluding vasculopathies? Part I: small vessel vasculopathies
por: Ratzinger, Gudrun, et al.
Publicado: (2019)

Bar Code Reader – an algorithmic approach to cutaneous occluding vasculopathies? part II medium vessel vasculopathies
por: Ratzinger, Gudrun, et al.
Publicado: (2019)

Hyperspectral Imaging as a Tool for Viability Assessment During Normothermic Machine Perfusion of Human Livers: A Proof of Concept Pilot Study
por: Fodor, Margot, et al.
Publicado: (2022)

Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice
por: Namas, Rami A., et al.
Publicado: (2013)

The spectrum of melanocytic nevi and their clinical implications
por: Frischhut, Nina, et al.
Publicado: (2022)

Disturbance rejection model predictive control of lower limb rehabilitation exoskeleton
por: Jin, Xin, et al.
Publicado: (2023)

Lymphocytes as an Indicator for Initial Kidney Function: A Single Center Analysis of Outcome after Alemtuzumab or Basiliximab Induction
por: Weissenbacher, Annemarie, et al.
Publicado: (2015)

Hyperspectral Imaging and Machine Perfusion in Solid Organ Transplantation: Clinical Potentials of Combining Two Novel Technologies
por: Fodor, Margot, et al.
Publicado: (2021)

Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis
por: Tyagi, Pradeep, et al.
Publicado: (2009)

Diagnostic Biomarkers to Diagnose Acute Allograft Rejection After Liver Transplantation: Systematic Review and Meta-Analysis of Diagnostic Accuracy Studies
por: Krenzien, Felix, et al.
Publicado: (2019)

Immunophenotypic characterization of human T cells after in vitro exposure to different silicone breast implant surfaces
por: Cappellano, Giuseppe, et al.
Publicado: (2018)

Time for trauma immunology
por: Billiar, Timothy R., et al.
Publicado: (2017)

Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome
por: Meszaros, Andras T., et al.
Publicado: (2022)

Novel, Innovative Models to Study Ischemia/Reperfusion-Related Redox Damage in Organ Transplantation
por: Hofmann, Julia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8u0fe2tmjh88nec8r5pf77k6go