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Study on Biopharmaceutics Classification and Oral Bioavailability of a Novel Multikinase Inhibitor NCE for Cancer Therapy

Specific biopharmaceutics classification investigation and study on phamacokinetic profile of a novel drug candidate (2-methylcarbamoyl-4-{4-[3- (trifluoromethyl) benzamido] phenoxy} pyridinium 4-methylbenzenesulfonate monohydrate, NCE) were carried out. Equilibrium solubility and intrinsic dissolut...

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Detalles Bibliográficos
Autores principales:	Yang, Yang, Fan, Chun-Mei, He, Xuan, Ren, Ke, Zhang, Jin-Kun, He, Ying-Ju, Yu, Luo-Ting, Zhao, Ying-Lan, Gong, Chang-Yang, Zheng, Yu, Song, Xiang-Rong, Zeng, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057667/ https://www.ncbi.nlm.nih.gov/pubmed/24776763 http://dx.doi.org/10.3390/ijms15057199

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