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Topical N-Acetylcysteine Accelerates Wound Healing in Vitro and in Vivo via the PKC/Stat3 Pathway
N-Acetylcysteine (Nac) is an antioxidant administered in both oral and injectable forms. In this study, we used Nac topically to treat burn wounds in vitro and in vivo to investigate mechanisms of action. In vitro, we monitored glutathione levels, cell proliferation, migration, scratch-wound healing...
Autores principales: | Tsai, Min-Ling, Huang, Hui-Pei, Hsu, Jeng-Dong, Lai, Yung-Rung, Hsiao, Yu-Ping, Lu, Fung-Jou, Chang, Horng-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057691/ https://www.ncbi.nlm.nih.gov/pubmed/24798751 http://dx.doi.org/10.3390/ijms15057563 |
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