Cargando…
Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions
Magnesium based implants could revolutionize applications where orthopedic implants such as nails, screws or bone plates are used because they are load bearing and degrade over time. This prevents a second surgery to remove conventional implants. To improve the biocompatibility we studied here if an...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057696/ https://www.ncbi.nlm.nih.gov/pubmed/24857908 http://dx.doi.org/10.3390/ijms15057639 |
_version_ | 1782321012555120640 |
---|---|
author | Willumeit, Regine Möhring, Anneke Feyerabend, Frank |
author_facet | Willumeit, Regine Möhring, Anneke Feyerabend, Frank |
author_sort | Willumeit, Regine |
collection | PubMed |
description | Magnesium based implants could revolutionize applications where orthopedic implants such as nails, screws or bone plates are used because they are load bearing and degrade over time. This prevents a second surgery to remove conventional implants. To improve the biocompatibility we studied here if and for how long a pre-incubation of the material under cell culture conditions is favorable for cell attachment and proliferation. For two materials, Mg and Mg10Gd1Nd, we could show that 6 h pre-incubation are already enough to form a natural protective layer suitable for cell culture. |
format | Online Article Text |
id | pubmed-4057696 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-40576962014-06-16 Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions Willumeit, Regine Möhring, Anneke Feyerabend, Frank Int J Mol Sci Article Magnesium based implants could revolutionize applications where orthopedic implants such as nails, screws or bone plates are used because they are load bearing and degrade over time. This prevents a second surgery to remove conventional implants. To improve the biocompatibility we studied here if and for how long a pre-incubation of the material under cell culture conditions is favorable for cell attachment and proliferation. For two materials, Mg and Mg10Gd1Nd, we could show that 6 h pre-incubation are already enough to form a natural protective layer suitable for cell culture. Molecular Diversity Preservation International (MDPI) 2014-05-05 /pmc/articles/PMC4057696/ /pubmed/24857908 http://dx.doi.org/10.3390/ijms15057639 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Willumeit, Regine Möhring, Anneke Feyerabend, Frank Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions |
title | Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions |
title_full | Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions |
title_fullStr | Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions |
title_full_unstemmed | Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions |
title_short | Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions |
title_sort | optimization of cell adhesion on mg based implant materials by pre-incubation under cell culture conditions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057696/ https://www.ncbi.nlm.nih.gov/pubmed/24857908 http://dx.doi.org/10.3390/ijms15057639 |
work_keys_str_mv | AT willumeitregine optimizationofcelladhesiononmgbasedimplantmaterialsbypreincubationundercellcultureconditions AT mohringanneke optimizationofcelladhesiononmgbasedimplantmaterialsbypreincubationundercellcultureconditions AT feyerabendfrank optimizationofcelladhesiononmgbasedimplantmaterialsbypreincubationundercellcultureconditions |