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Alpha-Bulges in G Protein-Coupled Receptors
Agonist binding is related to a series of motions in G protein-coupled receptors (GPCRs) that result in the separation of transmembrane helices III and VI at their cytosolic ends and subsequent G protein binding. A large number of smaller motions also seem to be associated with activation. Most heli...
Autores principales: | van der Kant, Rob, Vriend, Gert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057707/ https://www.ncbi.nlm.nih.gov/pubmed/24806342 http://dx.doi.org/10.3390/ijms15057841 |
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