Aryl Hydrocarbon Receptor Repressor and TiPARP (ARTD14) Use Similar, but also Distinct Mechanisms to Repress Aryl Hydrocarbon Receptor Signaling

The aryl hydrocarbon receptor (AHR) regulates the toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The AHR repressor (AHRR) is an AHR target gene and functions as a ligand-induced repressor of AHR; however, its mechanism of inhibition is controversial. Recently, we reported that TCDD-ind...

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Detalles Bibliográficos
Autores principales: MacPherson, Laura, Ahmed, Shaimaa, Tamblyn, Laura, Krutmann, Jean, Förster, Irmgard, Weighardt, Heike, Matthews, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057711/
https://www.ncbi.nlm.nih.gov/pubmed/24806346
http://dx.doi.org/10.3390/ijms15057939

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