Cargando…

The G Protein-Coupled Receptor Heterodimer Network (GPCR-HetNet) and Its Hub Components

G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner. However, despite the current development of experimental techni...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borroto-Escuela, Dasiel O., Brito, Ismel, Romero-Fernandez, Wilber, Di Palma, Michael, Oflijan, Julia, Skieterska, Kamila, Duchou, Jolien, Van Craenenbroeck, Kathleen, Suárez-Boomgaard, Diana, Rivera, Alicia, Guidolin, Diego, Agnati, Luigi F., Fuxe, Kjell
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057749/ https://www.ncbi.nlm.nih.gov/pubmed/24830558 http://dx.doi.org/10.3390/ijms15058570

Ejemplares similares

Evidence for the existence of dopamine D2R and Sigma 1 allosteric receptor-receptor interaction in the rat brain: role in brain plasticity and cocaine action
por: Pinton, Luca, et al.
Publicado: (2015)

Evidence for the existence of the A2A-A1 heteroreceptor complex in the rat brain, and comparison of its distribution to that of the A2A-A2A homoreceptor complex
por: Oflijan, Julia, et al.
Publicado: (2015)

Dopamine D(4) Receptor Counteracts Morphine-Induced Changes in μ Opioid Receptor Signaling in the Striosomes of the Rat Caudate Putamen
por: Suárez-Boomgaard, Diana, et al.
Publicado: (2014)

On the G-Protein-Coupled Receptor Heteromers and Their Allosteric Receptor-Receptor Interactions in the Central Nervous System: Focus on Their Role in Pain Modulation
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2013)

Diversity and Bias through Receptor–Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization
por: Fuxe, Kjell, et al.
Publicado: (2014)

Mapping the Interface of a GPCR Dimer: A Structural Model of the A(2A) Adenosine and D(2) Dopamine Receptor Heteromer
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2018)

Volume transmission and receptor-receptor interactions in heteroreceptor complexes: understanding the role of new concepts for brain communication
por: Fuxe, Kjell, et al.
Publicado: (2016)

Can Allosteric Receptor-Protein Interactions in Receptor Complexes Be a Molecular Mechanism Involved in Cancer Immune Therapy?
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

Adenosine heteroreceptor complexes in the basal ganglia are implicated in Parkinson’s disease and its treatment
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

Oligomeric Receptor Complexes and Their Allosteric Receptor-Receptor Interactions in the Plasma Membrane Represent a New Biological Principle for Integration of Signals in the CNS
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

On the G Protein-Coupled Receptor Neuromodulation of the Claustrum
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

The integrative role of G protein-coupled receptor heterocomplexes in Parkinson’s disease
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2022)

The oxytocin receptor represents a key hub in the GPCR heteroreceptor network: potential relevance for brain and behavior
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2022)

Molecular Integration in Adenosine Heteroreceptor Complexes Through Allosteric and De-Phosphorylation (STEP) Mechanisms and its Role in Brain Disease
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2022)

Increase of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems via allosteric receptor-receptor interaction
por: Borroto-Escuela, Dasiel O, et al.
Publicado: (2015)

Machine Learning Enabled Performance Prediction Model for Massive-MIMO HetNet System
por: Bandopadhaya, Shuvabrata, et al.
Publicado: (2021)

Potential of caveolae in the therapy of cardiovascular and neurological diseases
por: Navarro, Gemma, et al.
Publicado: (2014)

OSU-6162, a Sigma1R Ligand in Low Doses, Can Further Increase the Effects of Cocaine Self-Administration on Accumbal D2R Heteroreceptor Complexes
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2017)

On the role of A(2A) and D(2) receptors in control of cocaine and food-seeking behaviors in rats
por: Wydra, Karolina, et al.
Publicado: (2014)

A Survey on Handover and Mobility Management in 5G HetNets: Current State, Challenges, and Future Directions
por: Ullah, Yasir, et al.
Publicado: (2023)

Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2017)

Extrasynaptic Neurotransmission in the Modulation of Brain Function. Focus on the Striatal Neuronal–Glial Networks
por: Fuxe, Kjell, et al.
Publicado: (2012)

Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2018)

Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D(2) Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor
por: Vasudevan, Lakshmi, et al.
Publicado: (2019)

Speaker 4: Dasiel Borroto – Escuela, Sweden
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2016)

Acute Cocaine Enhances Dopamine D(2)R Recognition and Signaling and Counteracts D(2)R Internalization in Sigma1R-D(2)R Heteroreceptor Complexes
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

Adenosine A(2A)Receptors in Substance Use Disorders: A Focus on Cocaine
por: Wydra, Karolina, et al.
Publicado: (2020)

Differential allosteric modulation within dopamine D(2)R - neurotensin NTS1R and D(2)R - serotonin 5-HT(2A)R receptor complexes gives bias to intracellular calcium signalling
por: Plach, Michael, et al.
Publicado: (2019)

Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids
por: Spulber, Stefan, et al.
Publicado: (2019)

Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2016)

Receptor–Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2018)

On the existence and function of galanin receptor heteromers in the central nervous system
por: Fuxe, Kjell, et al.
Publicado: (2012)

Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2018)

Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2020)

Combined treatment with Sigma1R and A2AR agonists fails to inhibit cocaine self-administration despite causing strong antagonistic accumbal A2AR-D2R complex interactions: the potential role of astrocytes
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2023)

Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?
por: Beggiato, Sarah, et al.
Publicado: (2021)

5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression
por: Ambrogini, Patrizia, et al.
Publicado: (2023)

The mGlu(5) Receptor Protomer-Mediated Dopamine D(2) Receptor Trans-Inhibition Is Dependent on the Adenosine A(2A) Receptor Protomer: Implications for Parkinson’s Disease
por: Romero-Fernandez, Wilber, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_08d8er030g8lrm0t39en9uc3f0