An estrogen analogue and promising anticancer agent refrains from inducing morphological damage and reactive oxygen species generation in erythrocytes, fibrin and platelets: a pilot study

BACKGROUND: 2-Methoxyestradiol is known to have antitumour and antiproliferative action in vitro and in vivo. However, when 2-methoxyestradiol is orally administered, it is rapidly oxidized by the enzyme 17β-hydroxysteriod dehydrogenase in the gastrointestinal tract. Therefore, 2-methoxyestradiol n...

Descripción completa

Detalles Bibliográficos
Autores principales: Repsold, Lisa, Pretorius, Etheresia, Joubert, Annie Margaretha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057810/
https://www.ncbi.nlm.nih.gov/pubmed/24932135
http://dx.doi.org/10.1186/1475-2867-14-48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057810/
https://www.ncbi.nlm.nih.gov/pubmed/24932135
http://dx.doi.org/10.1186/1475-2867-14-48

Ejemplares similares