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An estrogen analogue and promising anticancer agent refrains from inducing morphological damage and reactive oxygen species generation in erythrocytes, fibrin and platelets: a pilot study

BACKGROUND: 2-Methoxyestradiol is known to have antitumour and antiproliferative action in vitro and in vivo. However, when 2-methoxyestradiol is orally administered, it is rapidly oxidized by the enzyme 17Î²-hydroxysteriod dehydrogenase in the gastrointestinal tract. Therefore, 2-methoxyestradiol n...

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Detalles Bibliográficos
Autores principales:	Repsold, Lisa, Pretorius, Etheresia, Joubert, Annie Margaretha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057810/ https://www.ncbi.nlm.nih.gov/pubmed/24932135 http://dx.doi.org/10.1186/1475-2867-14-48

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