Unique molecular signatures as a hallmark of patients with metastatic breast cancer: Implications for current treatment paradigms

Our analysis of the tumors of 57 women with metastatic breast cancer with next generation sequencing (NGS) demonstrates that each patient's tumor is unique in its molecular fingerprint. We observed 216 somatic aberrations in 70 different genes, including 131 distinct aberrations. The most commo...

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Detalles Bibliográficos
Autores principales: Wheler, Jennifer J., Parker, Barbara A., Lee, Jack J., Atkins, Johnique T., Janku, Filip, Tsimberidou, Apostolia M., Zinner, Ralph, Subbiah, Vivek, Fu, Siqing, Schwab, Richard, Moulder, Stacy, Valero, Vicente, Schwaederle, Maria, Yelensky, Roman, Miller, Vincent A., Stephens, M Philip J., Meric-Bernstam, Funda, Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058010/
https://www.ncbi.nlm.nih.gov/pubmed/24811890

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