Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resistance to olaparib, gamma radiation, and cisplatin

Indoleamine 2,3-dioxygenase-1 (IDO) is an immunosuppressive molecule expressed by most human tumors. IDO levels correlate with poor prognosis in cancer patients and IDO inhibitors are under investigation to enhance endogenous anticancer immunosurveillance. Little is known of immune-independent funct...

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Detalles Bibliográficos
Autores principales: Vareki, Saman Maleki, Rytelewski, Mateusz, Figueredo, Rene, Chen, Di, Ferguson, Peter J., Vincent, Mark, Min, Weiping, Zheng, Xiufen, Koropatnick, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058044/
https://www.ncbi.nlm.nih.gov/pubmed/24784564

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