Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups

One-hundred-fifty-three biliary cancers, including 70 intrahepatic cholangiocarcinomas (ICC), 57 extrahepatic cholangiocarcinomas (ECC) and 26 gallbladder carcinomas (GBC) were assessed for mutations in 56 genes using multigene next-generation sequencing. Expression of EGFR and mTOR pathway genes wa...

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Detalles Bibliográficos
Autores principales: Simbolo, Michele, Fassan, Matteo, Ruzzenente, Andrea, Mafficini, Andrea, Wood, Laura D., Corbo, Vincenzo, Melisi, Davide, Malleo, Giuseppe, Vicentini, Caterina, Malpeli, Giorgio, Antonello, Davide, Sperandio, Nicola, Capelli, Paola, Tomezzoli, Anna, Iacono, Calogero, Lawlor, Rita T., Bassi, Claudio, Hruban, Ralph H., Guglielmi, Alfredo, Tortora, Giampaolo, de Braud, Filippo, Scarpa, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058049/
https://www.ncbi.nlm.nih.gov/pubmed/24867389

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