Cargando…

Apoptosis Induction by the Total Flavonoids from Arachniodes exilis in HepG2 Cells through Reactive Oxygen Species-Mediated Mitochondrial Dysfunction Involving MAPK Activation

Arachniodes exilis is used as a folk medicine in China and proved to have antibacterial, anti-inflammatory, and sedative activities. In the present study, the antitumor effect of the total flavonoids of A. exilis (TFAE) against HepG2 cells was evaluated. The results showed that TFAE inhibited the gr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Huimin, Chen, Jing, Xiong, Chaomei, Wei, Han, Yin, Changchang, Ruan, Jinlan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058121/ https://www.ncbi.nlm.nih.gov/pubmed/24976852 http://dx.doi.org/10.1155/2014/906941

Ejemplares similares

Inhibition of Tumor Growth of Human Hepatocellular Carcinoma HepG2 Cells in a Nude Mouse Xenograft Model by the Total Flavonoids from Arachniodes exilis
por: Li, Huimin, et al.
Publicado: (2017)

Different effects of total flavonoids from Arachniodes exilis on human umbilical cord mesenchymal stem cells in vitro
por: Yu, Wenmin, et al.
Publicado: (2020)

Reactive oxygen species inhibits Listeria monocytogenes invasion into HepG2 epithelial cells
por: Chen, Guo‐wei, et al.
Publicado: (2018)

High quality genome assembly of the amitochondriate eukaryote Monocercomonoides exilis
por: Treitli, Sebastian Cristian, et al.
Publicado: (2021)

Diosgenin Induces Apoptosis in HepG2 Cells through Generation of Reactive Oxygen Species and Mitochondrial Pathway
por: Kim, Dae Sung, et al.
Publicado: (2012)

Radioprotective effect on HepG2 cells of low concentrations of cobalt chloride: induction of hypoxia-inducible factor-1 alpha and clearance of reactive oxygen species
por: Jin, Wensen, et al.
Publicado: (2013)

Induction of apoptosis by Xiakemycin A in human hepatoma HepG2 cells
por: Chen, Chuan, et al.
Publicado: (2020)

Reactive Oxygen Species Induces Lipid Droplet Accumulation in HepG2 Cells by Increasing Perilipin 2 Expression
por: Jin, Yi, et al.
Publicado: (2018)

Intracellular Toxic Advanced Glycation End-Products Promote the Production of Reactive Oxygen Species in HepG2 Cells
por: Sakasai-Sakai, Akiko, et al.
Publicado: (2020)

Grape Seed Proanthocyanidins Induce Apoptosis and Cell Cycle Arrest of HepG2 Cells Accompanied by Induction of the MAPK Pathway and NAG-1
por: Wang, Lihua, et al.
Publicado: (2020)

Preparation and characterization of zein–lecithin–total flavonoids from Smilax glabra complex nanoparticles and the study of their antioxidant activity on HepG2 cells
por: Li, Jing, et al.
Publicado: (2023)

Synthesis of Chalcone Derivatives: Inducing Apoptosis of HepG2 Cells via Regulating Reactive Oxygen Species and Mitochondrial Pathway
por: Zhu, Hongtian, et al.
Publicado: (2019)

RY10-4 Inhibits the Proliferation of Human Hepatocellular Cancer HepG2 Cells by Inducing Apoptosis In Vitro and In Vivo
por: Zhang, Xuenong, et al.
Publicado: (2016)

Induction of Apoptosis and Cytotoxicity by Isothiocyanate Sulforaphene in Human Hepatocarcinoma HepG2 Cells
por: Kntayya, Saie Brindha, et al.
Publicado: (2018)

Anti-adipogenic effect of the flavonoids through the activation of AMPK in palmitate (PA)-treated HepG2 cells
por: Rajan, Priyanka, et al.
Publicado: (2021)

Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen
por: Lai, Alvina G., et al.
Publicado: (2018)

Alyssin and Iberin in Cruciferous Vegetables Exert Anticancer Activity in HepG2 by Increasing Intracellular Reactive Oxygen Species and Tubulin Depolymerization
por: Pocasap, Piman, et al.
Publicado: (2019)

In vitro cytotoxicity and induction of apoptosis by silica nanoparticles in human HepG2 hepatoma cells
por: Lu, Xun, et al.
Publicado: (2011)

The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells
por: Ji, Chunxiao, et al.
Publicado: (2010)

Zerumbone suppresses the potential of growth and metastasis in hepatoma HepG2 cells via the MAPK signaling pathway
por: Lv, Tao, et al.
Publicado: (2018)

Hepatoprotective effects of flavonoids from common buckwheat hulls in type 2 diabetic rats and HepG2 cells
por: Wang, Hai, et al.
Publicado: (2021)

Anticancer Effect of Rh2, a Histone Deacetylase Inhibitor, in HepG2 Cells and HepG2 Cell-Derived Xenograft Tumors Occurs via the Inhibition of HDACs and Activation of the MAPK Signaling Pathway
por: Qiang, Shi Qing, et al.
Publicado: (2021)

Nutritional and physicochemical changes in two varieties of fonio (Digitaria exilis and Digitaria iburua) during germination
por: Bassey, Stella Oyom, et al.
Publicado: (2023)

Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways
por: Zhang, Chao, et al.
Publicado: (2016)

Anti-Inflammatory Effect of Protopine through MAPK and NF-κB Signaling Regulation in HepG2 Cell
por: Kim, MinGyu, et al.
Publicado: (2022)

Effect of total glycosides of Cistanche deserticola on the energy metabolism of human HepG2 cells
por: Feng, Duo, et al.
Publicado: (2023)

PKCα mediated induction of miR-101 in human hepatoma HepG2 cells
por: Chiang, Chao-Wei, et al.
Publicado: (2010)

Simultaneous induction of apoptosis and necroptosis by Tanshinone IIA in human hepatocellular carcinoma HepG2 cells
por: Lin, C-Y, et al.
Publicado: (2016)

Dose-Dependent Cytotoxic Effects of Boldine in HepG-2 Cells—Telomerase Inhibition and Apoptosis Induction
por: Kazemi Noureini, Sakineh, et al.
Publicado: (2015)

Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation
por: Hu, Die, et al.
Publicado: (2022)

Genome sequence and genetic diversity analysis of an under-domesticated orphan crop, white fonio (Digitaria exilis)
por: Wang, Xuewen, et al.
Publicado: (2021)

Artificial cells eavesdropping on HepG2 cells
por: Westensee, Isabella Nymann, et al.
Publicado: (2023)

Hesperidin Induces Paraptosis Like Cell Death in Hepatoblatoma, HepG2 Cells: Involvement of ERK1/2 MAPK
por: Yumnam, Silvia, et al.
Publicado: (2014)

Lanosterol synthase loss of function decreases the malignant phenotypes of HepG2 cells by deactivating the Src/MAPK signaling pathway
por: Sun, Xiaomei, et al.
Publicado: (2023)

Crambescin C1 Exerts a Cytoprotective Effect on HepG2 Cells through Metallothionein Induction
por: Roel, María, et al.
Publicado: (2015)

Antiproliferative Effect of the Isoquinoline Alkaloid Papaverine in Hepatocarcinoma HepG-2 Cells — Inhibition of Telomerase and Induction of Senescence
por: Noureini, Sakineh Kazemi, et al.
Publicado: (2014)

Induction of Apoptosis by Berberine in Hepatocellular Carcinoma HepG2 Cells via Downregulation of NF-κB
por: Li, Min, et al.
Publicado: (2017)

Influence of total polar compounds on lipid metabolism, oxidative stress and cytotoxicity in HepG2 cells
por: Ju, Jingjie, et al.
Publicado: (2019)

Qizhi Jiangtang Jiaonang Improves Insulin Signaling and Reduces Inflammatory Cytokine Secretion and Reactive Oxygen Species Formation in Insulin Resistant HepG2 Cells
por: Zhang, Xiao-Tian, et al.
Publicado: (2015)

Anti-tumor effect of volatile oil from Houttuynia cordata Thunb. on HepG2 cells and HepG2 tumor-bearing mice
por: Yang, Linsong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dfijjo0o5loiec4huhhb0u0scc