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Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers

End stage renal disease is a relatively frequent disease with high mortality due to cardiac causes. Permanent pacemaker (PM) implantation rates are also very common; thus combination of both conditions is not unusual. We hypothesized that patients with chronic kidney disease with a PM would have sig...

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Autores principales: Vanerio, Gabriel, García, Cristina, González, Carlota, Ferreiro, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058238/
https://www.ncbi.nlm.nih.gov/pubmed/24977040
http://dx.doi.org/10.1155/2014/284172
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author Vanerio, Gabriel
García, Cristina
González, Carlota
Ferreiro, Alejandro
author_facet Vanerio, Gabriel
García, Cristina
González, Carlota
Ferreiro, Alejandro
author_sort Vanerio, Gabriel
collection PubMed
description End stage renal disease is a relatively frequent disease with high mortality due to cardiac causes. Permanent pacemaker (PM) implantation rates are also very common; thus combination of both conditions is not unusual. We hypothesized that patients with chronic kidney disease with a PM would have significantly higher mortality rates compared with end stage renal disease patients without PM. Our objectives were to analyze mortality of patients on renal replacement therapy with PM. 2778 patients were on renal replacement therapy (RRT) and 110 had a PM implanted during the study period. To reduce the confounding effects of covariates, a propensity-matched score was performed. 52 PM patients and 208 non-PM matched patients were compared. 41% of the PM were implanted before entering the RRT program and 59% while on RRT. Mortality was higher in the PM group. Cardiovascular disease and infections were the most frequent causes of death. Propensity analysis showed no differences in long-term mortality between groups. We concluded that in patients on RRT and PM mortality rates are higher. Survival curves did not differ from a RRT propensity-matched group. We concluded that the presence of a PM is not an independent mortality risk factor in RRT patients.
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spelling pubmed-40582382014-06-29 Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers Vanerio, Gabriel García, Cristina González, Carlota Ferreiro, Alejandro Int J Nephrol Research Article End stage renal disease is a relatively frequent disease with high mortality due to cardiac causes. Permanent pacemaker (PM) implantation rates are also very common; thus combination of both conditions is not unusual. We hypothesized that patients with chronic kidney disease with a PM would have significantly higher mortality rates compared with end stage renal disease patients without PM. Our objectives were to analyze mortality of patients on renal replacement therapy with PM. 2778 patients were on renal replacement therapy (RRT) and 110 had a PM implanted during the study period. To reduce the confounding effects of covariates, a propensity-matched score was performed. 52 PM patients and 208 non-PM matched patients were compared. 41% of the PM were implanted before entering the RRT program and 59% while on RRT. Mortality was higher in the PM group. Cardiovascular disease and infections were the most frequent causes of death. Propensity analysis showed no differences in long-term mortality between groups. We concluded that in patients on RRT and PM mortality rates are higher. Survival curves did not differ from a RRT propensity-matched group. We concluded that the presence of a PM is not an independent mortality risk factor in RRT patients. Hindawi Publishing Corporation 2014 2014-05-26 /pmc/articles/PMC4058238/ /pubmed/24977040 http://dx.doi.org/10.1155/2014/284172 Text en Copyright © 2014 Gabriel Vanerio et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Vanerio, Gabriel
García, Cristina
González, Carlota
Ferreiro, Alejandro
Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_full Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_fullStr Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_full_unstemmed Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_short Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_sort mortality in patients on renal replacement therapy and permanent cardiac pacemakers
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058238/
https://www.ncbi.nlm.nih.gov/pubmed/24977040
http://dx.doi.org/10.1155/2014/284172
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