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The Early Activation of CD8(+) T Cells Is Dependent on Type I IFN Signaling following Intramuscular Vaccination of Adenovirus Vector
Few of the vaccines in current use can induce antigen- (Ag-) specific immunity in both mucosal and systemic compartments. Hence, the development of vaccines that realize both mucosal and systemic protection against various pathogens is a high priority in global health. Recently, it has been reported...
Autores principales: | Hemmi, Masahisa, Tachibana, Masashi, Tsuzuki, Sayaka, Shoji, Masaki, Sakurai, Fuminori, Kawabata, Kenji, Kobiyama, Kouji, Ishii, Ken J., Akira, Shizuo, Mizuguchi, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058243/ https://www.ncbi.nlm.nih.gov/pubmed/24971314 http://dx.doi.org/10.1155/2014/158128 |
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