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Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal cancer

BACKGROUND: 5-Fluorouracil (5-FU) is the cornerstone of chemotherapeutic treatment for patients with colorectal cancer. The enzyme thymidine phosphorylase (TP) catalyzes the conversion of 5-FU to its active metabolite, 5-fluoro-2’-deoxyuridine. TP is expressed in tumour epithelial cells and stromal...

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Detalles Bibliográficos
Autores principales:	Lindskog, Elinor Bexe, Derwinger, Kristoffer, Gustavsson, Bengt, Falk, Peter, Wettergren, Yvonne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058433/ https://www.ncbi.nlm.nih.gov/pubmed/24936150 http://dx.doi.org/10.1186/1472-6890-14-25

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