RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks

Psoriasis is a chronic inflammatory skin disease driven by aberrant signals from the immune system. In this issue Li et al. present the first large RNA-seq analysis of gene expression in normal skin and psoriasis lesions, providing a more comprehensive view of mRNA expression than earlier microarray...

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Detalles Bibliográficos
Autor principal: Quigley, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058644/
https://www.ncbi.nlm.nih.gov/pubmed/24924757
http://dx.doi.org/10.1038/jid.2014.66
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author Quigley, David
author_facet Quigley, David
author_sort Quigley, David
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description Psoriasis is a chronic inflammatory skin disease driven by aberrant signals from the immune system. In this issue Li et al. present the first large RNA-seq analysis of gene expression in normal skin and psoriasis lesions, providing a more comprehensive view of mRNA expression than earlier microarray studies. This study’s size enables gene co-expression analysis, a method illustrating which pathways are altered by the presence of disease.
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spelling pubmed-40586442015-01-01 RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks Quigley, David J Invest Dermatol Article Psoriasis is a chronic inflammatory skin disease driven by aberrant signals from the immune system. In this issue Li et al. present the first large RNA-seq analysis of gene expression in normal skin and psoriasis lesions, providing a more comprehensive view of mRNA expression than earlier microarray studies. This study’s size enables gene co-expression analysis, a method illustrating which pathways are altered by the presence of disease. 2014-07 /pmc/articles/PMC4058644/ /pubmed/24924757 http://dx.doi.org/10.1038/jid.2014.66 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Quigley, David
RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks
title RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks
title_full RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks
title_fullStr RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks
title_full_unstemmed RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks
title_short RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks
title_sort rna-seq permits a closer look at normal skin and psoriasis gene networks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058644/
https://www.ncbi.nlm.nih.gov/pubmed/24924757
http://dx.doi.org/10.1038/jid.2014.66
work_keys_str_mv AT quigleydavid rnaseqpermitsacloserlookatnormalskinandpsoriasisgenenetworks

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