In Vitro Inhibition of Hepatitis C Virus by Antisense Oligonucleotides in PBMC Compared to Hepatoma Cells

Aim. To assess the efficiency of phosphorothioate antisense oligodeoxynucleotide 1 (S-ODN1) on HCV translation inhibition in PBMC compared to hepatoma cells in vitro for the first time. Materials and Methods. The study included 34 treatment naive HCV patients. IRES domain III and IV sequence variati...

Descripción completa

Detalles Bibliográficos
Autores principales: Youssef, Samar Samir, Fahmy, Ahmed Mohamed, Omran, Moataza Hassan, Mohamed, Amr Saad, El Desouki, Mohamed Ali, El-Awady, Mostafa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058683/
https://www.ncbi.nlm.nih.gov/pubmed/24991538
http://dx.doi.org/10.1155/2014/196712

Ejemplares similares

Ejemplares similares