Cargando…

The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa

BACKGROUND: Retinitis pigmentosa (RP) is an inherited human retinal disorder that causes progressive photoreceptor cell loss, leading to severe vision impairment or blindness. However, no effective therapy has been established to date. Although genetic mutations have been identified, the available c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoshida, Tetsu, Ozawa, Yoko, Suzuki, Keiichiro, Yuki, Kenya, Ohyama, Manabu, Akamatsu, Wado, Matsuzaki, Yumi, Shimmura, Shigeto, Mitani, Kohnosuke, Tsubota, Kazuo, Okano, Hideyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058693/ https://www.ncbi.nlm.nih.gov/pubmed/24935155 http://dx.doi.org/10.1186/1756-6606-7-45

Ejemplares similares

Generation of Stratified Squamous Epithelial Progenitor Cells from Mouse Induced Pluripotent Stem Cells
por: Yoshida, Satoru, et al.
Publicado: (2011)

Generation of Human Melanocytes from Induced Pluripotent Stem Cells
por: Ohta, Shigeki, et al.
Publicado: (2011)

PM492. Schizophrenia patient-derived induced pluripotent stem cells exhibit changes in neurogenic and gliogenic competences
por: Toyoshima, Manabu, et al.
Publicado: (2016)

Roles of STAT3/SOCS3 Pathway in Regulating the Visual Function and Ubiquitin-Proteasome-dependent Degradation of Rhodopsin during Retinal Inflammation
por: Ozawa, Yoko, et al.
Publicado: (2008)

Effects of Epigenetic Modification of PGC-1α by a Chemical Chaperon on Mitochondria Biogenesis and Visual Function in Retinitis Pigmentosa
por: Ozawa, Yoko, et al.
Publicado: (2022)

AMPK-NF-κB Axis in the Photoreceptor Disorder during Retinal Inflammation
por: Kamoshita, Mamoru, et al.
Publicado: (2014)

The Semaphorin 3A inhibitor SM-345431 preserves corneal nerve and epithelial integrity in a murine dry eye model
por: Yamazaki, Risa, et al.
Publicado: (2017)

Skin‐Derived Precursors as a Source of Progenitors for Corneal Endothelial Regeneration
por: Inagaki, Emi, et al.
Publicado: (2017)

Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells
por: Fujii, Shota, et al.
Publicado: (2019)

MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model
por: Ogawa, Yoko, et al.
Publicado: (2016)

The Semaphorin 3A Inhibitor SM-345431 Accelerates Peripheral Nerve Regeneration and Sensitivity in a Murine Corneal Transplantation Model
por: Omoto, Masahiro, et al.
Publicado: (2012)

Regulation of Posttranscriptional Modification as a Possible Therapeutic Approach for Retinal Neuroprotection
por: Ozawa, Yoko, et al.
Publicado: (2011)

Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium
por: Homma, Kohei, et al.
Publicado: (2021)

Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells
por: Veraitch, Ophelia, et al.
Publicado: (2017)

Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells
por: Fujimori, Koki, et al.
Publicado: (2017)

Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model
por: Miyashita, Hideyuki, et al.
Publicado: (2017)

Renin-Angiotensin System Hyperactivation Can Induce Inflammation and Retinal Neural Dysfunction
por: Kurihara, Toshihide, et al.
Publicado: (2012)

Nucleostemin as a possible progenitor marker of corneal epithelial cells
por: Kawashima, Motoko, et al.
Publicado: (2009)

Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling
por: Matsumoto, Takuya, et al.
Publicado: (2016)

Retinal phototoxicity in a novel murine model of intraocular lens implantation
por: Kurihara, Toshihide, et al.
Publicado: (2009)

Four cases of corneal perforation in patients with chronic graft-versus-host disease
por: Inagaki, Emi, et al.
Publicado: (2011)

Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2
por: Yamazoe, Katsuya, et al.
Publicado: (2015)

The Anterior Eye Chamber as a Visible Medium for In Vivo Tumorigenicity Tests
por: Inagaki, Emi, et al.
Publicado: (2022)

Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophy
por: Sakakura, Saki, et al.
Publicado: (2023)

Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research
por: Yagi, Takuya, et al.
Publicado: (2012)

Angiotensin II Type 1 Receptor Antagonist Attenuates Lacrimal Gland, Lung, and Liver Fibrosis in a Murine Model of Chronic Graft-Versus-Host Disease
por: Yaguchi, Saori, et al.
Publicado: (2013)

Multivariable Logistic Regression Model: A Novel Mathematical Model that Predicts Visual Field Sensitivity from Macular Ganglion Cell Complex Thickness in Glaucoma
por: Shiba, Daisuke, et al.
Publicado: (2014)

Analysis of the Association between Galectin-3 Concentration in Tears and the Severity of Dry Eye Disease: A Case-Control Study
por: Hata-Mizuno, Miki, et al.
Publicado: (2021)

Neural Degeneration in the Retina of the Streptozotocin-Induced Type 1 Diabetes Model
por: Ozawa, Yoko, et al.
Publicado: (2011)

Comparison of telomere length and association with progenitor cell markers in lacrimal gland between Sjögren syndrome and non-Sjögren syndrome dry eye patients
por: Kawashima, Motoko, et al.
Publicado: (2011)

Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression
por: Nishihara, Koji, et al.
Publicado: (2019)

Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage
por: Andoh-Noda, Tomoko, et al.
Publicado: (2015)

MSCs Become Collagen-Type I Producing Cells with Different Phenotype in Allogeneic and Syngeneic Bone Marrow Transplantation
por: Rusch, Robert Maximilian, et al.
Publicado: (2021)

A Rabbit Corneal Endothelial Dysfunction Model Using Endothelial-Mesenchymal Transformed Cells
por: Yamashita, Kazuya, et al.
Publicado: (2018)

A human Dravet syndrome model from patient induced pluripotent stem cells
por: Higurashi, Norimichi, et al.
Publicado: (2013)

Expression and localization of aging markers in lacrimal gland of chronic graft-versus-host disease
por: Kawai, Masataka, et al.
Publicado: (2013)

Purified Mesenchymal Stem Cells Are an Efficient Source for iPS Cell Induction
por: Niibe, Kunimichi, et al.
Publicado: (2011)

Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes
por: Imaizumi, Kent, et al.
Publicado: (2015)

Modeling neurological diseases with induced pluripotent cells reprogrammed from immortalized lymphoblastoid cell lines
por: Fujimori, Koki, et al.
Publicado: (2016)

Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production
por: Uchino, Yuichi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_asrosdpobq4o2hl1affnibjuuq