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ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair

The peptidyl–prolyl cis/trans isomerase Pin1 acts as a molecular timer in proline-directed Ser/Thr kinase signaling and shapes cellular responses based on recognition of phosphorylation marks and implementing conformational changes in its substrates. Accordingly, Pin1 has been linked to numerous pho...

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Detalles Bibliográficos
Autores principales: Polonio-Vallon, Tilman, Krüger, Daniel, Hofmann, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058901/
https://www.ncbi.nlm.nih.gov/pubmed/24982848
http://dx.doi.org/10.3389/fonc.2014.00148

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