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ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair
The peptidyl–prolyl cis/trans isomerase Pin1 acts as a molecular timer in proline-directed Ser/Thr kinase signaling and shapes cellular responses based on recognition of phosphorylation marks and implementing conformational changes in its substrates. Accordingly, Pin1 has been linked to numerous pho...
Autores principales: | Polonio-Vallon, Tilman, Krüger, Daniel, Hofmann, Thomas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058901/ https://www.ncbi.nlm.nih.gov/pubmed/24982848 http://dx.doi.org/10.3389/fonc.2014.00148 |
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