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TLR9 Ligand (CpG Oligodeoxynucleotide) Induces CLL B-Cells to Differentiate into CD20(+) Antibody-Secreting Cells
B-cell chronic lymphocytic leukemia (CLL) is the most frequent adult leukemia in the Western world. It is a heterogeneous disease characterized by clonal proliferation and the accumulation of CD5(+) mature B lymphocytes. However, the normal counterpart from which the latter cells arise has not yet b...
Autores principales: | Ghamlouch, Hussein, Ouled-Haddou, Hakim, Guyart, Aude, Regnier, Aline, Trudel, Stéphanie, Claisse, Jean-François, Fuentes, Vincent, Royer, Bruno, Marolleau, Jean-Pierre, Gubler, Brigitte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058906/ https://www.ncbi.nlm.nih.gov/pubmed/24982661 http://dx.doi.org/10.3389/fimmu.2014.00292 |
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