Cargando…

Detecting independent and recurrent copy number aberrations using interval graphs

Motivation: Somatic copy number aberrations (SCNAs) are frequent in cancer genomes, but many of these are random, passenger events. A common strategy to distinguish functional aberrations from passengers is to identify those aberrations that are recurrent across multiple samples. However, the extens...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Hsin-Ta, Hajirasouliha, Iman, Raphael, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058951/
https://www.ncbi.nlm.nih.gov/pubmed/24931984
http://dx.doi.org/10.1093/bioinformatics/btu276