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Inferring gene ontologies from pairwise similarity data

Motivation: 1. analyze a full matrix of gene–gene pairwise similarities from -omics data; 2. infer true hierarchical structure in these data rather than enforcing hierarchy as a computational artifact; and 3. respect biological pleiotropy, by which a term in the hierarchy can relate to multiple high...

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Detalles Bibliográficos
Autores principales: Kramer, Michael, Dutkowski, Janusz, Yu, Michael, Bafna, Vineet, Ideker, Trey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058954/
https://www.ncbi.nlm.nih.gov/pubmed/24932003
http://dx.doi.org/10.1093/bioinformatics/btu282

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