Saccharomyces cerevisiae Essential Genes with an Opi(−) Phenotype

The overproduction and secretion of inositol (i.e., Opi(−)) phenotype is associated with defects in regulation of phospholipid biosynthesis in yeast. Here we report a screen of the essential yeast gene set using a conditional-expression library. This screen identified novel functions previously unkn...

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Detalles Bibliográficos
Autores principales: Salas-Santiago, Bryan, Lopes, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Mutant Screen Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059245/
https://www.ncbi.nlm.nih.gov/pubmed/24558266
http://dx.doi.org/10.1534/g3.113.010140
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author Salas-Santiago, Bryan
Lopes, John M.
author_facet Salas-Santiago, Bryan
Lopes, John M.
author_sort Salas-Santiago, Bryan
collection PubMed
description The overproduction and secretion of inositol (i.e., Opi(−)) phenotype is associated with defects in regulation of phospholipid biosynthesis in yeast. Here we report a screen of the essential yeast gene set using a conditional-expression library. This screen identified novel functions previously unknown to affect phospholipid synthesis.
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spelling pubmed-40592452014-06-16 Saccharomyces cerevisiae Essential Genes with an Opi(−) Phenotype Salas-Santiago, Bryan Lopes, John M. G3 (Bethesda) Mutant Screen Report The overproduction and secretion of inositol (i.e., Opi(−)) phenotype is associated with defects in regulation of phospholipid biosynthesis in yeast. Here we report a screen of the essential yeast gene set using a conditional-expression library. This screen identified novel functions previously unknown to affect phospholipid synthesis. Genetics Society of America 2014-02-20 /pmc/articles/PMC4059245/ /pubmed/24558266 http://dx.doi.org/10.1534/g3.113.010140 Text en Copyright © 2014 Salas-Santiago and Lopes http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Mutant Screen Report
Salas-Santiago, Bryan
Lopes, John M.
Saccharomyces cerevisiae Essential Genes with an Opi(−) Phenotype
title Saccharomyces cerevisiae Essential Genes with an Opi(−) Phenotype
title_full Saccharomyces cerevisiae Essential Genes with an Opi(−) Phenotype
title_fullStr Saccharomyces cerevisiae Essential Genes with an Opi(−) Phenotype
title_full_unstemmed Saccharomyces cerevisiae Essential Genes with an Opi(−) Phenotype
title_short Saccharomyces cerevisiae Essential Genes with an Opi(−) Phenotype
title_sort saccharomyces cerevisiae essential genes with an opi(−) phenotype
topic Mutant Screen Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059245/
https://www.ncbi.nlm.nih.gov/pubmed/24558266
http://dx.doi.org/10.1534/g3.113.010140
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AT lopesjohnm saccharomycescerevisiaeessentialgeneswithanopiphenotype

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