Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation

[Image: see text] An expeditious one-pot, ligand-free, Pd(OAc)(2)-catalyzed, three-component reaction for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines was developed under microwave irradiation. With the high availability of commercial reagents and great efficiency in expanding molecule diversi...

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Autores principales: Wang, Yuanxiang, Frett, Brendan, Li, Hong-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059256/
https://www.ncbi.nlm.nih.gov/pubmed/24854606
http://dx.doi.org/10.1021/ol501136e
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author Wang, Yuanxiang
Frett, Brendan
Li, Hong-yu
author_facet Wang, Yuanxiang
Frett, Brendan
Li, Hong-yu
author_sort Wang, Yuanxiang
collection PubMed
description [Image: see text] An expeditious one-pot, ligand-free, Pd(OAc)(2)-catalyzed, three-component reaction for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines was developed under microwave irradiation. With the high availability of commercial reagents and great efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines analogues.
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spelling pubmed-40592562015-05-22 Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation Wang, Yuanxiang Frett, Brendan Li, Hong-yu Org Lett [Image: see text] An expeditious one-pot, ligand-free, Pd(OAc)(2)-catalyzed, three-component reaction for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines was developed under microwave irradiation. With the high availability of commercial reagents and great efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines analogues. American Chemical Society 2014-05-22 2014-06-06 /pmc/articles/PMC4059256/ /pubmed/24854606 http://dx.doi.org/10.1021/ol501136e Text en Copyright © 2014 American Chemical Society
spellingShingle Wang, Yuanxiang
Frett, Brendan
Li, Hong-yu
Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation
title Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation
title_full Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation
title_fullStr Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation
title_full_unstemmed Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation
title_short Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation
title_sort efficient access to 2,3-diarylimidazo[1,2-a]pyridines via a one-pot, ligand-free, palladium-catalyzed three-component reaction under microwave irradiation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059256/
https://www.ncbi.nlm.nih.gov/pubmed/24854606
http://dx.doi.org/10.1021/ol501136e
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