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CoCl(2), a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in Colon Cancer
The induction of polyploidy is considered the reproductive end of cells, but there is evidence that polyploid giant cancer cells (PGCCs) contribute to cell repopulation during tumor relapse. However, the role of these cells in the development, progression and response to therapy in colon cancer rema...
Autores principales: | Lopez-Sánchez, Laura M., Jimenez, Carla, Valverde, Araceli, Hernandez, Vanessa, Peñarando, Jon, Martinez, Antonio, Lopez-Pedrera, Chary, Muñoz-Castañeda, Juan R., De la Haba-Rodríguez, Juan R., Aranda, Enrique, Rodriguez-Ariza, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059626/ https://www.ncbi.nlm.nih.gov/pubmed/24932611 http://dx.doi.org/10.1371/journal.pone.0099143 |
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