A Protein Data Bank Survey Reveals Shortening of Intermolecular Hydrogen Bonds in Ligand-Protein Complexes When a Halogenated Ligand Is an H-Bond Donor

Halogen bonding in ligand-protein complexes is currently widely exploited, e.g. in drug design or supramolecular chemistry. But little attention has been directed to other effects that may result from replacement of a hydrogen by a strongly electronegative halogen. Analysis of almost 30000 hydrogen...

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Detalles Bibliográficos
Autores principales: Poznański, Jarosław, Poznańska, Anna, Shugar, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059718/
https://www.ncbi.nlm.nih.gov/pubmed/24933273
http://dx.doi.org/10.1371/journal.pone.0099984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059718/
https://www.ncbi.nlm.nih.gov/pubmed/24933273
http://dx.doi.org/10.1371/journal.pone.0099984

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