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Insulin-Like Growth Factor 2 Silencing Restores Taxol Sensitivity in Drug Resistant Ovarian Cancer
Drug resistance is an obstacle to the effective treatment of ovarian cancer. We and others have shown that the insulin-like growth factor (IGF) signaling pathway is a novel potential target to overcome drug resistance. The purpose of this study was to validate IGF2 as a potential therapeutic target...
Autores principales: | Brouwer-Visser, Jurriaan, Lee, Jiyeon, McCullagh, KellyAnne, Cossio, Maria J., Wang, Yanhua, Huang, Gloria S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059749/ https://www.ncbi.nlm.nih.gov/pubmed/24932685 http://dx.doi.org/10.1371/journal.pone.0100165 |
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