A germline mutation in the BRCA1 3’UTR predicts Stage IV breast cancer

BACKGROUND: A germline, variant in the BRCA1 3’UTR (rs8176318) was previously shown to predict breast and ovarian cancer risk in women from high-risk families, as well as increased risk of triple negative breast cancer. Here, we tested the hypothesis that this variant predicts tumor biology, like ot...

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Detalles Bibliográficos
Autores principales: Dorairaj, Jemima J, Salzman, David W, Wall, Deirdre, Rounds, Tiffany, Preskill, Carina, Sullivan, Catherine AW, Lindner, Robert, Curran, Catherine, Lezon-Geyda, Kim, McVeigh, Terri, Harris, Lyndsay, Newell, John, Kerin, Michael J, Wood, Marie, Miller, Nicola, Weidhaas, Joanne B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059881/
https://www.ncbi.nlm.nih.gov/pubmed/24915755
http://dx.doi.org/10.1186/1471-2407-14-421

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