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Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation

The histone acetyltransferase (HAT) Mof is essential for mouse embryonic stem cell (mESC) pluripotency and early development. Mof is the enzymatic subunit of two different HAT complexes, MSL and NSL. The individual contribution of MSL and NSL to transcription regulation in mESCs is not well understo...

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Detalles Bibliográficos
Autores principales: Ravens, Sarina, Fournier, Marjorie, Ye, Tao, Stierle, Matthieu, Dembele, Doulaye, Chavant, Virginie, Tora, Làszlò
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059888/
https://www.ncbi.nlm.nih.gov/pubmed/24898753
http://dx.doi.org/10.7554/eLife.02104