Cargando…

eMERGEing progress in genomics—the first seven years

The electronic MEdical Records & GEnomics (eMERGE) network was established in 2007 by the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH) in part to explore the utility of electronic medical records (EMRs) in genome science. The initial focus was on di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crawford, Dana C., Crosslin, David R., Tromp, Gerard, Kullo, Iftikhar J., Kuivaniemi, Helena, Hayes, M. Geoffrey, Denny, Joshua C., Bush, William S., Haines, Jonathan L., Roden, Dan M., McCarty, Catherine A., Jarvik, Gail P., Ritchie, Marylyn D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060012/ https://www.ncbi.nlm.nih.gov/pubmed/24987407 http://dx.doi.org/10.3389/fgene.2014.00184

Ejemplares similares

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants
por: Verma, Anurag, et al.
Publicado: (2016)

Controlling for population structure and genotyping platform bias in the eMERGE multi-institutional biobank linked to electronic health records
por: Crosslin, David R., et al.
Publicado: (2014)

Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network
por: Hall, Molly A, et al.
Publicado: (2015)

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
por: Gottesman, Omri, et al.
Publicado: (2013)

The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies
por: McCarty, Catherine A, et al.
Publicado: (2011)

Genetic Variants Associated with Serum Thyroid Stimulating Hormone (TSH) Levels in European Americans and African Americans from the eMERGE Network
por: Malinowski, Jennifer R., et al.
Publicado: (2014)

Return of results in the genomic medicine projects of the eMERGE network
por: Kullo, Iftikhar J., et al.
Publicado: (2014)

Prospective participant selection and ranking to maximize actionable pharmacogenetic variants and discovery in the eMERGE Network
por: Crosslin, David R., et al.
Publicado: (2015)

Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network
por: Gallego, Carlos J., et al.
Publicado: (2015)

Mechanistic Phenotypes: An Aggregative Phenotyping Strategy to Identify Disease Mechanisms Using GWAS Data
por: Mosley, Jonathan D., et al.
Publicado: (2013)

Imputation and quality control steps for combining multiple genome-wide datasets
por: Verma, Shefali S., et al.
Publicado: (2014)

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network
por: Zhang, Xinyuan, et al.
Publicado: (2019)

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium
por: Verma, Shefali Setia, et al.
Publicado: (2016)

Electronic medical records and genomics (eMERGE) network exploration in cataract: Several new potential susceptibility loci
por: Ritchie, Marylyn D., et al.
Publicado: (2014)

ePhenotyping for Abdominal Aortic Aneurysm in the Electronic Medical Records and Genomics (eMERGE) Network: Algorithm Development and Konstanz Information Miner Workflow
por: Borthwick, Kenneth M, et al.
Publicado: (2015)

Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network
por: Bush, WS, et al.
Publicado: (2016)

Heritability and genome-wide association study of benign prostatic hyperplasia (BPH) in the eMERGE network
por: Hellwege, Jacklyn N., et al.
Publicado: (2019)

Evaluation of the MC4R gene across eMERGE network identifies many unreported obesity-associated variants
por: Namjou, Bahram, et al.
Publicado: (2020)

Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection
por: Ferar, Kathleen, et al.
Publicado: (2023)

Author Correction: Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection
por: Ferar, Kathleen, et al.
Publicado: (2023)

Practical considerations in genomic decision support: The eMERGE experience
por: Herr, Timothy M., et al.
Publicado: (2015)

Knowledge-Driven Multi-Locus Analysis Reveals Gene-Gene Interactions Influencing HDL Cholesterol Level in Two Independent EMR-Linked Biobanks
por: Turner, Stephen D., et al.
Publicado: (2011)

Loci identified by a genome‐wide association study of carotid artery stenosis in the eMERGE network
por: Palmer, Melody R., et al.
Publicado: (2020)

Design and Anticipated Outcomes of the eMERGE-PGx Project: A Multi-Center Pilot for Pre-Emptive Pharmacogenomics in Electronic Health Record Systems
por: Rasmussen-Torvik, Laura J., et al.
Publicado: (2014)

Frequency of genomic incidental findings among 21,915 eMERGE network participants
por: Gordon, Adam S., et al.
Publicado: (2020)

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index
por: Cronin, Robert M., et al.
Publicado: (2014)

GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network
por: Namjou, Bahram, et al.
Publicado: (2019)

The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype
por: Stanaway, Ian B., et al.
Publicado: (2018)

Genetic Variants That Confer Resistance to Malaria Are Associated with Red Blood Cell Traits in African-Americans: An Electronic Medical Record-based Genome-Wide Association Study
por: Ding, Keyue, et al.
Publicado: (2013)

A GWAS Study on Liver Function Test Using eMERGE Network Participants
por: Namjou, Bahram, et al.
Publicado: (2015)

Enhancing the Power of Genetic Association Studies through the Use of Silver Standard Cases Derived from Electronic Medical Records
por: McDavid, Andrew, et al.
Publicado: (2013)

Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders
por: Zhang, Xinyuan, et al.
Publicado: (2022)

Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort
por: Rosenthal, Elisabeth A., et al.
Publicado: (2021)

Genetic variation in the HLA region is associated with susceptibility to herpes zoster
por: Crosslin, D R, et al.
Publicado: (2015)

Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases
por: Verma, Anurag, et al.
Publicado: (2016)

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers
por: Mosley, Jonathan D., et al.
Publicado: (2018)

The foundation of precision medicine: integration of electronic health records with genomics through basic, clinical, and translational research
por: Ritchie, Marylyn D., et al.
Publicado: (2015)

Genome-wide study of resistant hypertension identified from electronic health records
por: Dumitrescu, Logan, et al.
Publicado: (2017)

Admixture Mapping and Subsequent Fine-Mapping Suggests a Biologically Relevant and Novel Association on Chromosome 11 for Type 2 Diabetes in African Americans
por: Jeff, Janina M., et al.
Publicado: (2014)

Returning Results in the Genomic Era: Initial Experiences of the eMERGE Network
por: Wiesner, Georgia L., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8r1f3jukdbeqsct6k0in1flmom