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Mechanisms of Resistance to Hsp90 Inhibitor Drugs: A Complex Mosaic Emerges
The molecular chaperone Hsp90 holds great promise as a cancer drug target, despite some of the initial clinical trials of Hsp90 inhibitor drugs having not lived up to expectation. Effective use of these drugs will benefit greatly from a much more detailed understanding of the factors that contribute...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060131/ https://www.ncbi.nlm.nih.gov/pubmed/27721330 http://dx.doi.org/10.3390/ph4111400 |