Blood-brain barrier damages and intrathecal synthesis of anti-N-methyl-D-aspartate receptor NR2 antibodies in diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematosus

INTRODUCTION: Although neuropsychiatric systemic lupus erythematosus (NPSLE) is one of the recalcitrant complications of the disease, its pathogenesis still remains unclear. Previous studies revealed that antibodies reactive with NMDA (N-methyl-D-aspartate) receptor NR2 (anti-NR2) are elevated in ce...

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Detalles Bibliográficos
Autores principales: Hirohata, Shunsei, Arinuma, Yoshiyuki, Yanagida, Tamiko, Yoshio, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060173/
https://www.ncbi.nlm.nih.gov/pubmed/24655341
http://dx.doi.org/10.1186/ar4518

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