Cargando…

Blocking the janus-activated kinase pathway reduces tumor necrosis factor alpha-induced interleukin-18 bioactivity by caspase-1 inhibition

INTRODUCTION: Our objective was to examine the role of the janus-activated kinase (JAK) pathway in the modulation of tumor necrosis factor-α (TNF)-induced-IL-18 bioactivity by reduction of caspase-1 function. METHODS: Caspase-1 expression in rheumatoid arthritis (RA) synovial fibroblasts treated wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marotte, Hubert, Tsou, Pei-Suen, Fedorova, Tatiana, Pinney, Adam J, Lewis, Benjamin, Koch, Alisa E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060193/ https://www.ncbi.nlm.nih.gov/pubmed/24762050 http://dx.doi.org/10.1186/ar4551

Ejemplares similares

Interleukin-18 as an in vivo mediator of monocyte recruitment in rodent models of rheumatoid arthritis
por: Ruth, Jeffrey H, et al.
Publicado: (2010)

Circulating tumour necrosis factor-α bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical response
por: Marotte, Hubert, et al.
Publicado: (2005)

Tumor Necrosis Factor-Alpha and Interleukin 6 in Human Periapical Lesions
por: Pršo, Ivana Brekalo, et al.
Publicado: (2007)

Tumor Necrosis Factor-Alpha and Interleukin-1 Alpha as Predictors of Survival in Peritonitis: A Pilot Study
por: Afuwape, Oludolapo Ola, et al.
Publicado: (2018)

Clozapine-induced cardiotoxicity in rats: Involvement of tumour necrosis factor alpha, NF-κβ and caspase-3
por: Abdel-Wahab, Basel A., et al.
Publicado: (2014)

Interleukin 17A: a Janus-faced regulator of osteoporosis
por: Scheffler, J. M., et al.
Publicado: (2020)

Methotrexate Reduced TNF Bioactivity in Rheumatoid Arthritis Patients Treated with Infliximab
por: Dénarié, Delphine, et al.
Publicado: (2017)

Tumour necrosis factor-alpha and interleukin-8 inhibit neutrophil migration in vitro and in vivo
por: Cunha, F. Q., et al.
Publicado: (1992)

Plasma Levels of Tumor Necrosis Factor-Alpha and Interleukin-6 in Obsessive Compulsive Disorder
por: Konuk, N., et al.
Publicado: (2007)

Tumor necrosis factor-alpha/interleukin-10 balance in normal and cystic fibrosis children.
por: Shmarina, G V, et al.
Publicado: (2001)

Interleukin 1 potentiates the lethal effect of tumor necrosis factor alpha/cachectin in mice
Publicado: (1988)

Tumor necrosis factor alpha/cachectin and interleukin 1 beta initiate meningeal inflammation
Publicado: (1990)

Interleukin 10 and Tumor Necrosis Factor-Alpha in Pregnancy: Aspects of Interest in Clinical Obstetrics
por: Brogin Moreli, Jusciele, et al.
Publicado: (2012)

Placental damage comparison between preeclampsia with COVID-19, COVID-19, and preeclampsia: analysis of caspase-3, caspase-1, and tumor necrosis factor-alpha expression
por: Bachnas, Muhammad Adrianes, et al.
Publicado: (2023)

Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response
Publicado: (1989)

Salivary and serum interleukin 1 beta, interleukin 6 and tumor necrosis factor alpha in patients with leukoplakia and oral cancer
por: Brailo, Vlaho, et al.
Publicado: (2012)

Janus All‐Cis 2,3,4,5,6‐Pentafluorocyclohexyl Building Blocks Applied to Medicinal Chemistry and Bioactives Discovery Chemistry
por: Clark, Joshua L., et al.
Publicado: (2021)

Blocking caspase-independent death
por: LeBrasseur, Nicole
Publicado: (2002)

Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts
por: Tsou, Pei-Suen, et al.
Publicado: (2014)

Inhibitory effects of bisbenzylisoquinolines on synthesis of the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha
por: Seow, W. Kim, et al.
Publicado: (1993)

Determination of Interleukin-6 and Tumor Necrosis Factor-alpha concentrations in Iranian-Khorasanian patients with preeclampsia
por: Afshari, J Tavakkol, et al.
Publicado: (2005)

The Levels of Tumor Necrosis Factor-Alpha and Interleukin-6 in Patients with Isolated Coronary Artery Ectasia
por: Aydin, Mustafa, et al.
Publicado: (2009)

Serum interleukin-1beta and tumor necrosis factor-alpha in febrile seizures: is there a link?
por: Mahyar, Abolfazl, et al.
Publicado: (2014)

Interleukin-8 and tumor necrosis factor-alpha in youth with mood disorders—A longitudinal study
por: Skibinska, Maria, et al.
Publicado: (2022)

CASPASE 8 inhibits programmed necrosis by processing CYLD
por: O’Donnell, Marie Anne, et al.
Publicado: (2011)

Effect of soluble interleukin-6 receptor alpha and interleukin-6 secreted by polymorphonuclear leukocytes on tumor necrosis factor-alpha expression and its production by peripheral blood mononuclear cells.
por: Jablonska, E
Publicado: (2002)

Serum levels of tumor necrosis factor-alpha, interleukin-6 and interleukin-8 are not increased in dyspeptic patients with Helicobacter pylori-associated gastritis.
por: Bayraktaroğlu, Taner, et al.
Publicado: (2004)

The effects of peritoneal dialysis and hemodialysis on serum tumor necrosis factor-alpha, interleukin-6, interleukin-10 and C-reactive-protein levels.
por: Borazan, Ali, et al.
Publicado: (2004)

Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases
por: Floss, Doreen M., et al.
Publicado: (2016)

Tumour necrosis factor-alpha enhances the cytolytic and cytostatic capacity of interleukin-2 activated killer cells.
por: Matossian-Rogers, A., et al.
Publicado: (1989)

Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction
Publicado: (1994)

Effect of Exercise Training on Interleukin-6, Tumour Necrosis Factor Alpha and Functional Capacity in Heart Failure
por: Smart, Neil A., et al.
Publicado: (2011)

Association of C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 with chronic kidney disease
por: Lee, Belinda T., et al.
Publicado: (2015)

Curcumin half analog modulates interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease
por: Kondamudi, Phani Krishna, et al.
Publicado: (2015)

Evaluation of serum level of tumor necrosis factor-alpha and interleukin-6 in patients with congenital heart disease
por: Noori, Noor Mohammad, et al.
Publicado: (2016)

Tumor Necrosis Factor-Alpha and Interleukin-6 Gene Polymorphisms in Iranian Patients with Ischemic Heart Failure
por: Hedayat, Mona, et al.
Publicado: (2018)

Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis
por: Noor, Zannatun, et al.
Publicado: (2017)

Exercise-induced downregulation of serum interleukin-6 and tumor necrosis factor-alpha in Egyptian handball players
por: Amin, Mohamed N., et al.
Publicado: (2021)

The use of anti-interleukin-1 agents and tumor necrosis factor‐alpha inhibitors in renal transplant recipients
por: Yazısız, Veli, et al.
Publicado: (2021)

Serum Levels of Interleukin-6 and Tumor Necrosis Factor Alpha in Children With Attention-Deficit Hyperactivity Disorder
por: Elsadek, Akram E., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_aqd9ble018sj9tuhq1ad025bhs