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Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism

INTRODUCTION: Sex hormones, especially estrogens, have been implicated in articular cartilage metabolism and the pathogenesis of postmenopausal osteoarthritis. The conversion by aromatase (CYP19A1) of androstenedione into estrone (E1) and of testosterone into 17β-estradiol (E2) plays a key role in t...

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Detalles Bibliográficos
Autores principales:	Schicht, Martin, Ernst, Jana, Nielitz, Andrea, Fester, Lars, Tsokos, Michael, Guddat, Saskia S, Bräuer, Lars, Bechmann, Judith, Delank, Karl-Stefan, Wohlrab, David, Paulsen, Friedrich, Claassen, Horst
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060203/ https://www.ncbi.nlm.nih.gov/pubmed/24725461 http://dx.doi.org/10.1186/ar4539

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