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Glut4 expression defines an insulin-sensitive hypothalamic neuronal population

Insulin signaling in the CNS modulates satiety and glucose metabolism, but insulin target neurons are poorly defined. We have previously shown that ablation of insulin receptors (InsR) in Glut4-expressing tissues results in systemic abnormalities of insulin action. We propose that Glut4 neurons cons...

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Detalles Bibliográficos
Autores principales: Ren, Hongxia, Yan, Shijun, Zhang, Baifang, Lu, Taylor Y., Arancio, Ottavio, Accili, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060214/
https://www.ncbi.nlm.nih.gov/pubmed/24944904
http://dx.doi.org/10.1016/j.molmet.2014.04.006

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