Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation

Cryptococcosis is the most common cause of meningitis in Africa due to the high burden of HIV. Immune reconstitution inflammatory syndrome (IRIS) is a frequent and deadly complication of cryptococcal meningitis. We report a fatal case of cryptococcal-IRIS in a pregnant woman that began after startin...

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Autores principales: Kiggundu, Reuben, Rhein, Joshua, Meya, David B., Boulware, David R., Bahr, Nathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060260/
https://www.ncbi.nlm.nih.gov/pubmed/24944885
http://dx.doi.org/10.1016/j.mmcr.2014.05.001
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author Kiggundu, Reuben
Rhein, Joshua
Meya, David B.
Boulware, David R.
Bahr, Nathan C.
author_facet Kiggundu, Reuben
Rhein, Joshua
Meya, David B.
Boulware, David R.
Bahr, Nathan C.
author_sort Kiggundu, Reuben
collection PubMed
description Cryptococcosis is the most common cause of meningitis in Africa due to the high burden of HIV. Immune reconstitution inflammatory syndrome (IRIS) is a frequent and deadly complication of cryptococcal meningitis. We report a fatal case of cryptococcal-IRIS in a pregnant woman that began after starting antiretroviral therapy (unmasking IRIS) and markedly worsened postpartum after delivery (paradoxical IRIS).
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spelling pubmed-40602602014-06-18 Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation Kiggundu, Reuben Rhein, Joshua Meya, David B. Boulware, David R. Bahr, Nathan C. Med Mycol Case Rep Article Cryptococcosis is the most common cause of meningitis in Africa due to the high burden of HIV. Immune reconstitution inflammatory syndrome (IRIS) is a frequent and deadly complication of cryptococcal meningitis. We report a fatal case of cryptococcal-IRIS in a pregnant woman that began after starting antiretroviral therapy (unmasking IRIS) and markedly worsened postpartum after delivery (paradoxical IRIS). Elsevier 2014-05-29 /pmc/articles/PMC4060260/ /pubmed/24944885 http://dx.doi.org/10.1016/j.mmcr.2014.05.001 Text en © 2014 International Society for Human and Animal Mycology http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Kiggundu, Reuben
Rhein, Joshua
Meya, David B.
Boulware, David R.
Bahr, Nathan C.
Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation
title Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation
title_full Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation
title_fullStr Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation
title_full_unstemmed Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation
title_short Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation
title_sort unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by hiv antiretroviral therapy with postpartum paradoxical exacerbation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060260/
https://www.ncbi.nlm.nih.gov/pubmed/24944885
http://dx.doi.org/10.1016/j.mmcr.2014.05.001
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