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Modulation of Antigen-Specific T-Cells as Immune Therapy for Chronic Infectious Diseases and Cancer
T-cell responses are induced by antigen presenting cells (APC) and signals from the microenvironment. Antigen persistence and inflammatory microenvironments in chronic infections and cancer can induce a tolerant state in T-cells resulting in hyporesponsiveness, loss of effector function, and weak bi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060297/ https://www.ncbi.nlm.nih.gov/pubmed/24987395 http://dx.doi.org/10.3389/fimmu.2014.00293 |