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Assessment of changes in the brca2 and p53 genes in breast invasive ductal carcinoma in northeast Brazil

BACKGROUND: BRCA protein interacts with at least 13 different proteins that have been implicated with cancer susceptibility and loss of BRCA function is correlated to sensitivity to DNA crosslinking agents in preclinical models. RESULTS: BRCA2 methylation frequency was 44%, p53 Pro22 allele frequenc...

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Detalles Bibliográficos
Autores principales:	Ramalho, Eduardo AVF, Silva-Filho, João LQ, Cartaxo, Marina FS, Cavalcanti, Carmelita BL, Rêgo, Moacyr JBM, Oliveira, Maria BM, Beltrão, Eduardo IC
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060371/ https://www.ncbi.nlm.nih.gov/pubmed/25027116 http://dx.doi.org/10.1186/0717-6287-47-3

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