Lack of validation of genetic variants associated with anti–tumor necrosis factor therapy response in rheumatoid arthritis: a genome-wide association study replication and meta-analysis

INTRODUCTION: In this study, our aim was to elucidate the role of four polymorphisms identified in a prior large genome-wide association study (GWAS) in which the investigators analyzed the responses of patients with rheumatoid arthritis (RA) to treatment with tumor necrosis factor inhibitors (TNFi)...

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Detalles Bibliográficos
Autores principales: Márquez, Ana, Ferreiro-Iglesias, Aida, Dávila-Fajardo, Cristina L, Montes, Ariana, Pascual-Salcedo, Dora, Perez-Pampin, Eva, Moreno-Ramos, Manuel J, García-Portales, Rosa, Navarro, Federico, Moreira, Virginia, Magro, César, Caliz, Rafael, Ferrer, Miguel Angel, Alegre-Sancho, Juan José, Joven, Beatriz, Carreira, Patricia, Balsa, Alejandro, Vasilopoulos, Yiannis, Sarafidou, Theologia, Cabeza-Barrera, José, Narvaez, Javier, Raya, Enrique, Cañete, Juan D, Fernández-Nebro, Antonio, Ordóñez, María del Carmen, de la Serna, Arturo R, Magallares, Berta, Gomez-Reino, Juan J, González, Antonio, Martín, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060376/
https://www.ncbi.nlm.nih.gov/pubmed/24612463
http://dx.doi.org/10.1186/ar4504

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