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How to build an inducible cartilage-specific transgenic mouse

Transgenic mice are used to study the roles of specific proteins in an intact living system. Use of transgenic mice to study processes in cartilage, however, poses some challenges. First of all, many factors involved in cartilage homeostasis and disease are also crucial factors in embryogenesis. The...

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Detalles Bibliográficos
Autores principales: Davidson, Esmeralda N Blaney, van de Loo, Fons AJ, van den Berg, Wim B, van der Kraan, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060449/
https://www.ncbi.nlm.nih.gov/pubmed/25166474
http://dx.doi.org/10.1186/ar4573