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Analgesic strategies aimed at stimulating the endogenous production of allopregnanolone
A growing number of studies indicate that 3-alpha reduced neurosteroids are remarkable analgesics in various pain states. This is the case for allopregnanolone (AP), one of the most potent endogenous positive allosteric modulators of GABA(A) receptor function. From the pioneering work of Hans Selye,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060572/ https://www.ncbi.nlm.nih.gov/pubmed/24987335 http://dx.doi.org/10.3389/fncel.2014.00174 |