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Different roles of alpha and beta band oscillations in anticipatory sensorimotor gating

Alpha (8–12 Hz) and beta band (18–30 Hz) oscillations have been implicated in sensory anticipation and motor preparation. Here, using magneto-encephalography, we tested whether they have distinct functional roles in a saccade task that induces a remapping between sensory and motor reference frames....

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Autores principales: Buchholz, Verena N., Jensen, Ole, Medendorp, W. Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060639/
https://www.ncbi.nlm.nih.gov/pubmed/24987348
http://dx.doi.org/10.3389/fnhum.2014.00446
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author Buchholz, Verena N.
Jensen, Ole
Medendorp, W. Pieter
author_facet Buchholz, Verena N.
Jensen, Ole
Medendorp, W. Pieter
author_sort Buchholz, Verena N.
collection PubMed
description Alpha (8–12 Hz) and beta band (18–30 Hz) oscillations have been implicated in sensory anticipation and motor preparation. Here, using magneto-encephalography, we tested whether they have distinct functional roles in a saccade task that induces a remapping between sensory and motor reference frames. With a crossed hands posture, subjects had to saccade as fast and accurate as possible toward a tactile stimulus delivered to one of two non-visible index fingers, located to the left or right of gaze. Previous studies have shown that this task, in which the somatotopic stimulus must be remapped to activate oculomotor system in the opposing hemisphere, is occasionally preceded by intrahemispheric remapping, driving a premature saccade into the wrong direction. To test whether the brain could anticipate the remapping, we provided auditory predictive cues (80% validity), which indicated which finger is most likely to be stimulated. Both frequency bands showed different lateralization profiles at central vs. posterior sensors, indicating anticipation of somatosensory and oculomotor processing. Furthermore, beta band power in somatosensory cortex correlated positively with saccade reaction time (SRT), with correlation values that were significantly higher with contralateral vs. ipsilateral activation. In contrast, alpha band power in parietal cortex correlated negatively with SRT, with correlation values that were significantly more negative with ipsilateral than contralateral activation. These results suggest distinct functional roles of beta and alpha band activity: (1) somatosensory gating by beta oscillations, increasing excitability in contralateral somatosensory cortex (positive correlation); and (2) oculomotor gating by posterior alpha oscillations, inhibiting gaze-centered oculomotor regions involved in generating the saccade to the wrong direction (negative correlation). Our results show that low frequency rhythms gate upcoming sensorimotor transformations.
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spelling pubmed-40606392014-07-01 Different roles of alpha and beta band oscillations in anticipatory sensorimotor gating Buchholz, Verena N. Jensen, Ole Medendorp, W. Pieter Front Hum Neurosci Neuroscience Alpha (8–12 Hz) and beta band (18–30 Hz) oscillations have been implicated in sensory anticipation and motor preparation. Here, using magneto-encephalography, we tested whether they have distinct functional roles in a saccade task that induces a remapping between sensory and motor reference frames. With a crossed hands posture, subjects had to saccade as fast and accurate as possible toward a tactile stimulus delivered to one of two non-visible index fingers, located to the left or right of gaze. Previous studies have shown that this task, in which the somatotopic stimulus must be remapped to activate oculomotor system in the opposing hemisphere, is occasionally preceded by intrahemispheric remapping, driving a premature saccade into the wrong direction. To test whether the brain could anticipate the remapping, we provided auditory predictive cues (80% validity), which indicated which finger is most likely to be stimulated. Both frequency bands showed different lateralization profiles at central vs. posterior sensors, indicating anticipation of somatosensory and oculomotor processing. Furthermore, beta band power in somatosensory cortex correlated positively with saccade reaction time (SRT), with correlation values that were significantly higher with contralateral vs. ipsilateral activation. In contrast, alpha band power in parietal cortex correlated negatively with SRT, with correlation values that were significantly more negative with ipsilateral than contralateral activation. These results suggest distinct functional roles of beta and alpha band activity: (1) somatosensory gating by beta oscillations, increasing excitability in contralateral somatosensory cortex (positive correlation); and (2) oculomotor gating by posterior alpha oscillations, inhibiting gaze-centered oculomotor regions involved in generating the saccade to the wrong direction (negative correlation). Our results show that low frequency rhythms gate upcoming sensorimotor transformations. Frontiers Media S.A. 2014-06-17 /pmc/articles/PMC4060639/ /pubmed/24987348 http://dx.doi.org/10.3389/fnhum.2014.00446 Text en Copyright © 2014 Buchholz, Jensen and Medendorp. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Buchholz, Verena N.
Jensen, Ole
Medendorp, W. Pieter
Different roles of alpha and beta band oscillations in anticipatory sensorimotor gating
title Different roles of alpha and beta band oscillations in anticipatory sensorimotor gating
title_full Different roles of alpha and beta band oscillations in anticipatory sensorimotor gating
title_fullStr Different roles of alpha and beta band oscillations in anticipatory sensorimotor gating
title_full_unstemmed Different roles of alpha and beta band oscillations in anticipatory sensorimotor gating
title_short Different roles of alpha and beta band oscillations in anticipatory sensorimotor gating
title_sort different roles of alpha and beta band oscillations in anticipatory sensorimotor gating
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060639/
https://www.ncbi.nlm.nih.gov/pubmed/24987348
http://dx.doi.org/10.3389/fnhum.2014.00446
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