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Effects of the Angiotensin Receptor Blocker Olmesartan on Adipocyte Hypertrophy and Function in Mice with Metabolic Disorders

In the present study, we examined the therapeutic effects of olmesartan, an angiotensin II (Ang II) type 1 receptor (AT1R)-specific blocker, in genetically obese diabetic KKAy mice, a model of human metabolic disorders with visceral obesity, with a focus on an olmesartan effect on the adipose tissue...

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Detalles Bibliográficos
Autores principales: Maeda, Akinobu, Tamura, Kouichi, Wakui, Hiromichi, Ohsawa, Masato, Azushima, Kengo, Uneda, Kazushi, Kanaoka, Tomohiko, Kobayashi, Ryu, Ohki, Kohji, Matsuda, Miyuki, Tsurumi-Ikeya, Yuko, Yamashita, Akio, Tokita, Yasuo, Umemura, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060760/
https://www.ncbi.nlm.nih.gov/pubmed/24991574
http://dx.doi.org/10.1155/2014/946492