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Effects of the Angiotensin Receptor Blocker Olmesartan on Adipocyte Hypertrophy and Function in Mice with Metabolic Disorders
In the present study, we examined the therapeutic effects of olmesartan, an angiotensin II (Ang II) type 1 receptor (AT1R)-specific blocker, in genetically obese diabetic KKAy mice, a model of human metabolic disorders with visceral obesity, with a focus on an olmesartan effect on the adipose tissue...
Autores principales: | Maeda, Akinobu, Tamura, Kouichi, Wakui, Hiromichi, Ohsawa, Masato, Azushima, Kengo, Uneda, Kazushi, Kanaoka, Tomohiko, Kobayashi, Ryu, Ohki, Kohji, Matsuda, Miyuki, Tsurumi-Ikeya, Yuko, Yamashita, Akio, Tokita, Yasuo, Umemura, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060760/ https://www.ncbi.nlm.nih.gov/pubmed/24991574 http://dx.doi.org/10.1155/2014/946492 |
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