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Characterization of the Deoxyguanosine–Lysine Cross-Link of Methylglyoxal

[Image: see text] Methylglyoxal is a mutagenic bis-electrophile that is produced endogenously from carbohydrate precursors. Methylglyoxal has been reported to induce DNA–protein cross-links (DPCs) in vitro and in cultured cells. Previous work suggests that these cross-links are formed between guanin...

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Detalles Bibliográficos
Autores principales:	Petrova, Katya V., Millsap, Amy D., Stec, Donald F., Rizzo, Carmelo J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060920/ https://www.ncbi.nlm.nih.gov/pubmed/24801980 http://dx.doi.org/10.1021/tx500068v

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