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OccuPeak: ChIP-Seq Peak Calling Based on Internal Background Modelling

ChIP-seq has become a major tool for the genome-wide identification of transcription factor binding or histone modification sites. Most peak-calling algorithms require input control datasets to model the occurrence of background reads to account for local sequencing and GC bias. However, the GC-cont...

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Detalles Bibliográficos
Autores principales: de Boer, Bouke A., van Duijvenboden, Karel, van den Boogaard, Malou, Christoffels, Vincent M., Barnett, Phil, Ruijter, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061025/
https://www.ncbi.nlm.nih.gov/pubmed/24936875
http://dx.doi.org/10.1371/journal.pone.0099844

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