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A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells
The human blood brain barrier (BBB) is a selective barrier formed by human brain endothelial cells (hBECs), which is important to ensure adequate neuronal function and protect the central nervous system (CNS) from disease. The development of human in vitro BBB models is thus of utmost importance for...
Autores principales: | Cecchelli, Romeo, Aday, Sezin, Sevin, Emmanuel, Almeida, Catarina, Culot, Maxime, Dehouck, Lucie, Coisne, Caroline, Engelhardt, Britta, Dehouck, Marie-Pierre, Ferreira, Lino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061029/ https://www.ncbi.nlm.nih.gov/pubmed/24936790 http://dx.doi.org/10.1371/journal.pone.0099733 |
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