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ATM Regulates Insulin-Like Growth Factor 1-Secretory Clusterin (IGF-1-sCLU) Expression that Protects Cells against Senescence

Downstream factors that regulate the decision between senescence and cell death have not been elucidated. Cells undergo senescence through three pathways, replicative senescence (RS), stress-induced premature senescence (SIPS) and oncogene-induced senescence. Recent studies suggest that the ataxia t...

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Detalles Bibliográficos
Autores principales: Luo, Xiuquan, Suzuki, Masatoshi, Ghandhi, Shanaz A., Amundson, Sally A., Boothman, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061041/
https://www.ncbi.nlm.nih.gov/pubmed/24937130
http://dx.doi.org/10.1371/journal.pone.0099983